邁向精確醫療(Toward Precision Medicine)

2015/04/21     來源:Harvard Magazine閱讀原文

What is biomedical informatics, why does it matter, and why now at HMS? The emerging discipline “reflects the dramatic development of large data sets in genetics, genomics, studies of proteins, the nervous system—all aspects of biomedical science and ultimately patient care,” says Gilbert Omenn, M.D. ’65, director of the University of Michigan’s Center for Computational Medicine and Bioinformatics, who chaired the external committee that reviewed the proposal for the new department. But much of this information is “heterogeneous,” he explains: the data range from the molecular and genetic to the behavioral and sociological. “All of it,” Omenn says, “has to come together to paint a complete picture of the determinants of health and disease, as well as response to therapies and general care.” Biomedical informatics aims to create an information commons that will be useful to researchers, doctors, and even their patients. Kohane’s experience as director of informatics at Boston Children’s Hospital, and at HMS’s Countway Library (see “Gutenberg 2.0,” May-June 2010, page 36), is directly pertinent.... more